Histone demethylase - 搜索结果

找到约 8 条 “Histone demethylase” 相关结果（用时 0.174 秒）

目录号	产品名称	中文名称	靶点
M6143	SP2509	SP2509	Histone demethylase
	HCI-2509
	SP2509是一种选择性histone demethylase LSD1抑制剂，SP2509 也是有效，选择性的 LSD1 拮抗剂，IC50为 13 nM，对MAO-A，MAO-B，乳酸脱氢酶和葡萄糖氧化酶没有活性。
M6259	CP2	CP2	Histone demethylase
	CP2是一种环肽，能够抑制JmjC histone demethylases KDM4，对KDM4A和KDM4C的IC50分别为42 nM和29 nM。
M8299	Methylstat	Methylstat	Others
	Methylstat is an inhibitor of the Jumonji C domain-containing histone trimethyl demethylases (JHDMs).
M9526	GSK-J5	GSK-J5	Histone demethylase
	GSK J5
	GSK-J5 is a cell-permeable, inactive control for histone demethylase JMJD3/UTX inhibitor GSK-J4.
M20864	L-2-Hydroxyglutaric acid disodium	L-2-Hydroxyglutaric acid disodium	Histone demethylase
	(S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG
	L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L-2-Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi-CK) with Km and Ki of 2.52 mM and 11.13 mM, respectively.
M21329	Histone H2A (1-20)	Histone H2A (1-20)	Peptides
	Histone H2A (1-20) 是一种含 35 个氨基酸的组蛋白 H2A 肽片段，是甲基转移酶/脱甲基酶 (methyltransferase/demethylase enzymes) 的底物。序列：Ser-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Ala-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-Arg。
M29846	α-Hydroxyglutaric acid	α-Hydroxyglutaric acid	Histone demethylase
	2-Hydroxyglutarate; 2-Hydroxyglutaric acid; 2-Hydroxypentanedioic acid
	α-Hydroxyglutaric acid (2-Hydroxyglutarate) 是戊二酸的 α-羟基酸形式。α-Hydroxyglutaric acid 是多种 α-酮戊二酸依赖性双加氧酶 (包括 histone demethylases 和 5-甲基胞嘧啶羟化酶 (5-methlycytosine (5mC) hydroxylases) 的 TET 家族) 的竞争性抑制剂。
M30059	α-Hydroxyglutaric acid disodium	α-Hydroxyglutaric acid disodium	Histone demethylase
	2-Hydroxyglutarate disodium; 2-Hydroxyglutaric acid disodium; 2-Hydroxypentanedioic acid disodium
	α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium 是戊二酸的 α-羟基酸形式。α-Hydroxyglutaric acid disodium 是多种 α-酮戊二酸依赖性双加氧酶 (包括 histone demethylases 和 5-甲基胞嘧啶羟化酶 (5-methlycytosine (5mC) hydroxylases) 的 TET 家族) 的竞争性抑制剂。

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